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Oral/Pharyngeal Cancer

Cancer Graphic What is it?
What puts me at risk?
Preventing Cancer
Screening for Early Detection
Treatment Options
Coping with Cancer
Statistics
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What is it?

  • Oral and oropharyngeal cancer include cancer of the lip, tongue, floor of the mouth, palate, gingiva and alveolar mucosa, buccal mucosa, and oropharynx. Oral and oropharyngeal cancers are the sixth most common cancer among white males and the fourth most common among black males. Males are approximately twice as likely as females to be diagnosed with and to die from oral and oropharyngeal cancer. Males have traditionally had higher incidence rates than females in New Jersey, although in recent years the gap is narrowing due to the increasing number of women who began smoking over the past three decades
  • More than 90% of oral cancers are squamous cell carcinoma. About 5% are salivary gland malignancies, and smaller percentages are melanomas, sarcomas, and lymphomas. The primary focus of a cancer control program for oral and oropharyngeal cancers must, therefore, be on squamous cell carcinoma, the predominant type.

What puts me at risk?

The known risk factors for oral and oropharyngeal squamous cell carcinoma are log-term tobacco use, alcohol use, immunosuppression, use of betel (areca) quid popular in Asian population, and in the case of lip cancer, long-tern sun exposure.

  • Use of tobacco. Tobacco can damage cells in the lining of the oral cavity and upper throat. Smokers are six times more likely than nonsmokers to develop oral or upper throat cancers. About 90 percent of people who develop these cancers use some form of tobacco. People who use smokeless tobacco are at high risk of cancers of the cheek and inner surface of the lips.
  • Excessive alcohol consumption. Alcohol also can damage cells inside your mouth and upper throat. About 75 percent to 80 percent of people with oral and upper throat cancers are frequent drinkers of alcohol. The combination of alcohol and tobacco use adds to the risk.
  • Prolonged exposure to ultraviolet light. Too much ultraviolet light can damage the cells on your lips and increase your risk of lip cancer.
  • Leukoplakia (white patches on the inside of the cheek or tongue). Most of the time leukoplakia is not dangerous. But leukoplakia can be serious, as some of the patches may show early signs of cancer, and a large percentage of cancers of the mouth occur in areas in which leukoplakia is adjacent. Leukoplakia may result from a variety of causes, including smoking or chewing tobacco products, ill-fitting dentures, a rough spot on an adjacent tooth or cheek-biting.

    For more information, log onto:
    MayoClinic.com


Preventing Cancer

Other steps you can take to help prevent oral cancer or to prevent its progression include:

  • See your dentist annually for a check-up, especially if you are at high risk for oral cancer and ask for an oral cancer screening.
  • Use well-fitting dentures. If you wear dentures, be sure they fit properly and are well cleaned and rinsed. Oral irritation increases your risk of oral cancer.
  • Don't chew on the inside of your mouth. Doing so also irritates your oral tissues.
  • Limit your exposure to the sun. Ultraviolet light damages the skin on your lips and increases your risk of cancer. When you're out in the sun, use lip balm and a wide-brimmed hat to protect your face, including your lips.

    Check your mouth and tongue periodically. Standing in front of a mirror, use your forefinger and thumb to pull facial tissue aside to get a good view of the tissue on the inside of your lips, your cheeks and elsewhere inside your mouth. Look for bumps and for changes in color. Use your thumbs and fingers to check for lumps and tender spots. If you notice changes, talk to your dentist or doctor. Oral cancer is curable. But success depends on detecting it early.

    For more information on preventing cancer, log onto:
    MayoClinic.com


Screening for Early Detection

  • Oral Exam – Ask for an oral cancer screening. Screening for oral cancer may be done during a physical exam by the dentist or doctor. The areas of the mouth that are inspected for early detection are: the floor of the mouth, the front and sides of the tongue, and the soft palate . During the exam, t he doctor or dentist will pull out your tongue, sometimes with gauze wrapped around it, and feel under the tongue , inside the cheeks , and your neck.

    For more information on oral cancer screening, log onto :
    Mayo Foundation for Medical Education and Research
    National Cancer Institute – Oral Cancer Screening

Treatment Options

  • Surgery -The type of surgery you may need depends on the size and location of the tumor. The tumors that have invaded nearby tissues, surgery is more extensive. Sometimes surgeons need to remove bone tissue from the jaw or roof of the mouth. To treat a cancer of your tongue or the upper part of your throat, your surgeon may need to remove tissues that you use to swallow and in some cases your voice box (larynx). If the cancer has spread beyond your mouth, your surgeon also may need to remove lymph nodes in your neck.
  • Radiation therapy- Radiation therapy uses X-rays to kill cancer cells. This approach also may be used along with surgery to destroy small amounts of cancer cells that couldn't be removed during surgery.
  • Chemotherapy- Chemotherapy uses drugs to destroy cancer cells. You take these drugs either through your veins (intravenously) or orally. The type of drugs and the length of treatment depend on the size and location of the tumor. Chemotherapy may be used before surgery in order to shrink a tumor. Or, in the case of a large and invasive tumor, chemotherapy may be used in combination with radiation therapy and in place of surgery.
  • Reconstructive surgery- The goal of reconstructive surgery is to improve your appearance and to help you adjust to difficulties you may have chewing, swallowing, speaking or breathing. Sometimes you'll need grafts of skin or other tissue from other parts of your body to rebuild areas in your mouth, throat or jaw. If you've had extensive surgery in your neck, you may also undergo surgery to create a hole in your neck (tracheostomy) to help you breathe more easily. If muscles you need for swallowing have been removed, you'll need surgery to create a hole in your abdomen (gastrostomy) in order to receive food directly into your stomach through a feeding tube.
  • Rehabilitation- Adjusting to life after your surgery may mean working with a speech therapist and dietitian. A speech therapist can help you overcome problems with speech and eating. If you've lost the ability to speak, you can learn to speak by forcing air up through your esophagus (esophageal speech). Artificial devices also are available to help you speak or speak more loudly. A dietitian can help you choose foods that are suitable for you if you've lost some of your ability to chew and swallow. In addition, you may benefit from sessions with a physical therapist and occupational therapist to help you make adjustments in your personal and work lives.

    For more information about treatment options, log onto:
    MayoClinic.com

    For information on finding a doctor or treatment facility, log onto: http://www.cancer.gov/cancertopics/factsheet/Therapy/doctor-facility


    Clinical Trials

Coping with Cancer

    Palliative Care - Comprehensive Cancer Control Plan

    • Palliative care is a coordinated, inter-disciplinary approach to healthcare that enhances the quality of life of patients with cancer and other illnesses. It targets the physical and psychological symptoms and spiritual needs of patients from the time of diagnosis to end-of-life care in all settings.

    For more information on Palliative Care , log onto:
    The World Oncology Network
    StopPain.org
    New Jersey Hospice and Palliative Care Organization

    Children Coping with Parents with Oral & Oropharyngeal Cancer

    • Learn more about all different types of cancers.
    • Questions that children might have dealing with cancer.
    • Books to help children understand more about certain cancers.
    • Stories from other children.
    • Camps and foundations.

    For more information, log onto:
    CancerSourceKids


Statistics

Comprehensive Cancer Control Plan
National Center for Health Statistics NCHS- Fact Sheets
New Jersey State Cancer Registry

More Information


Department of Health and Senior Services

P. O. Box 360, Trenton, NJ 08625-0360
Phone: (609) 292-7837
Toll-free in NJ: 1-800-367-6543
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Last Modified: Thursday, 20-Nov-08 11:49:52