Sample Analysis and Methods
Scientists analyze samples for many reasons, including:
to assist targeted public health investigations to see if people were exposed to an environmental chemical contamination;
to identify spatial and temporal differences in population exposure;
to provide public health policy evaluation and intervention evaluation for disease diagnosis and rapid response; and
to monitor that potentially harmful chemicals remain at safe levels among a population or select subpopulations and establish baseline exposure levels.
|
Target Compounds |
Matrix |
Method |
Instrument |
|
Metals |
Blood |
CDC DLS 3016.8-03 |
ICP-DRC-MS |
|
Mercury Species |
Blood |
CDC DLS 3020 |
TSID-GC-ICP-DRC-MS |
|
Metals |
Urine |
CDC DLS 3018.4-02 for elements CDC DLS 3018A.3-02 for total arsenic |
ICP-DRC-MS |
|
Arsenic Species |
Urine |
CDC DLS 3000.15 |
HPLC-ICP-DRC-MS |
|
Mercury |
Urine |
CDC DLS 3002.7-04 |
ICP-DRC-MS |
|
Per- and Polyfluoroalkyl Substances (PFAS) |
Serum |
Modified from CDC DLS 6304.04 |
Online SPE-HPLC-MS/MS |
|
Polychlorinated Biphenyls (PCBs) |
Serum |
CDC DLS 6701.04 |
HRGC-HRMS |
|
Polybrominated Diphenyl Ethers (PBDEs) |
Serum |
CDC DLS 6701.04 |
HRGC-HRMS |
|
Organochlorine Pesticides (OCPs) |
Serum |
CDC DLS 6701.04 |
HRGC-HRMS |
|
Polycyclic Aromatic Hydrocarbon (PAH) Metabolites |
Urine |
CDC DLS 6705.02 |
Online SPE-HPLC-MS/MS |
|
Volatile Organic Compound (VOC) Metabolites |
Urine |
CDC Method for VOC metabolites |
UHPLC-MS/MS |
|
Nicotine Metabolites |
Serum |
CDC DLS 2017 |
SLE-HPLC-MS/MS |
|
Metals |
Dried Blood Spot |
Under Development |
ICP-DRC-MS |
|
PCBs+OCPs |
Dried Blood Spot |
Under Development |
HRGC-HRMS |
