Official Site of The State of New Jersey
Explore FDA-approved COVID-19 treatments, including antiviral medications. Learn who is eligible and how these treatments help prevent severe illness and reduce hospitalization risks.
Key Takeaways:
- If you are at risk of severe illness from COVID-19, begin antiviral treatment as soon as symptoms appear.
- All antiviral treatments require a prescription from a health care provider or pharmacist.
- Use the Treatment Locator (hhs.gov) to find testing, treatment locations, or pharmacies near you.
Understanding COVID-19 Treatments
Managing Mild COVID-19 Symptoms
Most mild COVID-19 cases can be managed with over-the-counter medications such as ibuprofen or acetaminophen.
FDA-Approved Antivirals
If you test positive for COVID-19, starting FDA-approved antivirals, like Paxlovid or Remdesivir, within 5–7 days of symptom onset can significantly reduce the risk of severe illness. These treatments have been widely used and have helped millions avoid serious COVID-19 symptoms and hospital stays.
Important: Antiviral medications require a prescription from a health care provider or pharmacist.
Who's at Higher Risk for Severe Illness?
Certain groups are at higher risk for severe illness from COVID-19, including:
- Adults aged 65 and older.
- Individuals who are unvaccinated or not up to date with COVID-19 vaccinations
- People with chronic health conditions, such as lung disease, heart disease, or weakened immune systems.
Antiviral Therapies
The FDA has approved several antiviral treatments for people with mild to moderate COVID-19 who are at risk of severe illness. Antivirals must be prescribed by a health care provider or pharmacist.
- Use the Treatment Locator (hhs.gov) to find locations offering testing, treatment, and pharmacy services.
- For people with weakened immune systems, your health care provider may recommend additional treatment options if you experience ongoing symptoms after initial antiviral treatment, including therapies like convalescent plasma.
Antiviral Treatment Options
The following treatments are available and can be accessed based on eligibility, treatment timing, and administration method:
Antiviral
Nirmatrelvir with Ritonavir (Paxlovid)
Who Can Take It
Adults and Children 12 years and older
When
Start as soon as possible; treatment must begin within 5 days of first symptoms
How
Oral tablets taken at home
Antiviral
Remdesivir (Veklury)
Who Can Take It
Adults and Children
When
Start as soon as possible; treatment must begin within 7 days of first symptoms
How
Administered through intravenous (IV) infusions at a healthcare facility for 3 consecutive days
Antiviral
Molnupiravir (Lagevrio)
Who Can Take It
Adults
When
Start as soon as possible; treatment must begin within 5 days of first symptoms
How
Oral tablets taken at home
Important Considerations
- Staying up to date on COVID-19 vaccinations greatly reduces the likelihood of severe illness, hospitalization, or death.
- If you’re taking other medications, consult your health care provider or pharmacist to ensure COVID-19 treatments can be taken safely alongside them.
Questions to Ask Your Health Care Provider
Before starting any antiviral treatment, consider discussing the following questions with your health care provider to ensure safety and efficacy:
- Will Paxlovid interact with any other medicines I'm taking?
- Will Veklury interact with any other medicines I'm taking?
- Should I be concerned about my renal or hepatic (liver) impairment?
- Will taking an oral antiviral impact my birth control?
- Is it safe to take an oral antiviral if I am pregnant or breastfeeding?
Frequently Asked Questions
If you test positive for COVID-19 and have symptoms, you may be eligible for antiviral treatment. Treatment is especially recommended for individuals at higher risk of severe illness, including older adults, unvaccinated individuals, and those with underlying health conditions. Always consult a health care provider to assess your situation and determine the best course of action.
Common side effects of COVID-19 antiviral medications can include:
- Nausea
- Diarrhea
- Dizziness
- Headaches
More severe side effects are less common but can occur. Discuss potential side effects with your health care provider before starting any new medication.
If you are pregnant or breastfeeding, consult your health care provider before starting any COVID-19 medication. While some treatments may be safe, a health care professional can offer guidance based on the latest research and your specific health needs.